Application of enteral nutrition support via naso-jejunal tube in esophageal carcinoma patients treated with ;radiotheraphy
10.3760/cma.j.issn.1008-6706.2017.02.018
- VernacularTitle:经鼻肠管肠内营养支持在食管癌放疗患者中的应用
- Author:
Guiqiong XU
;
Minying LI
;
Feng LEI
;
Yijing YE
;
Yuhai BAI
;
Yuxiu OUYANG
;
Jiaxiong ZHOU
- Keywords:
Esophageal neoplasms;
Enteral nutrition
- From:
Chinese Journal of Primary Medicine and Pharmacy
2017;24(2):228-230,231
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of enteral nutrition support via naso-jejunal tube in esopha-geal carcinoma patients treated with radiotheraphy.Methods 36 esophageal carcinoma patients were randomly assigned into enteral nutrition(EN)group,while 38 patients assigned to control group.All patients underwent defini-tion IMRT combined with weekly concurrent chemotherapy of paclitaxel-nedaplatin.The naso -jejunal tubes were bedside inserted by hand in EN group.Enteral nutrition support began the day after the tube insertion.The control group took food orally.Nutrition was assessed through body weight,BMI,lymphocyte,albumin,pre -albumin and hemoglobin.Treatment induced complications were recorded.Results The degree of nutritional reduction was lower in EN group and significantly different with the control group.The EN group underwent (4.5 ±1 .1 )cycles concurrent chemotherapy,the control group underwent (3.1 ±2.3)cycles concurrent chemotherapy(t=6.21,P=0.027).The hematotoxicity induced by chemoradiotherapy(CRT)was statistically severe in the control group(χ2 =24.64,P<0.01),while radiation esophagitis was similar between the two groups.Conclusion EN support via naso -jejunal tube in esophageal carcinoma patients treated with radiotheraphy may improve the nutritional status,alleviate CRT induced hematotoxicity,increase tolerance of CRT.
