Research progress on role of Wnt signaling pathway in regulation of tumors
10.3969/j.issn.1001-1978.2017.01.003
- VernacularTitle:Wnt信号通路在肿瘤调控方面的研究进展
- Author:
Shiping ZHANG
;
Xu ZHANG
- Keywords:
Wnt signaling pathway;
β-catenin;
Adenomatous polyposis coli protein;
regulation of signaling pathway;
mecha-nism;
tumor
- From:
Chinese Pharmacological Bulletin
2017;33(1):14-17,18
- CountryChina
- Language:Chinese
-
Abstract:
Wnt signaling pathway is a highly conservative signal pathway controlling cell growth,differentiation,apoptosis and self-renewal.This signal pathway is often abnormally activated in tumor development and progression,which can cooperate or antagonize with other signal pathways to regulate tumor prolifera-tion,migration and invasion.This paper makes a review of the recent research of Wnt signaling pathway progression and its function in tumor growth regulation.
