The research progress of nanomedicine for immunomodulation therapy
10.3969/j.issn.1001-1978.2017.02.003
- VernacularTitle:纳米药物免疫调节治疗的研究进展
- Author:
Xuefeng WANG
;
Liang TANG
;
Jun WANG
;
Yang SHU
;
Yi WANG
- Keywords:
nanomedicine;
immunomodulation;
therapy;
re-search progress;
autoimmune;
inflammation
- From:
Chinese Pharmacological Bulletin
2017;33(2):158-160,161
- CountryChina
- Language:Chinese
-
Abstract:
Recent studies have showed that nanotechnology pro-vides a new revolution for the treatment of complex,refractory autoimmune or inflammatory diseases.Nanoparticles combined with specific autoantigens can restore the peripheral tolerance and reduce immunopathological damage in a variety of autoimmune disease models.In this paper,we review the progress and trends of nanomedcine for treatment of autoimmune or inflammatory dis-eases as immunomodulatory therapy from the physical and chemi-cal characteristics of nanoparticles,the route of administration, and the role and mechanism of induction or reconstitution of im-mune tolerance,which provides a theoretical basis for seeking new treatments to treat inflammatory diseases.
