Research Progress in the Influencing Factors in Particles Uptaking of Alveolar Macrophages
- VernacularTitle:肺泡巨噬细胞摄取微粒作用影响因素的研究进展
- Author:
Yanming WANG
;
Qingqing ZHAO
;
Lili CHE
;
Hongmei LIU
;
Xiaona LIU
;
Jinfeng JIAO
;
Jingling TANG
- Keywords:
Pulmonary drug delivery;
Pulmonary macrophage;
Particles;
Uptaking action
- From:
China Pharmacist
2017;20(1):151-153,197
- CountryChina
- Language:Chinese
-
Abstract:
Pulmonary drug delivery has become a research focus in recent years, while the action between particles and pulmonary macrophages after particles transportation to lung tissue was paid little attention. Therapeutic efficacy can be enhanced by regulating the particles uptake action of pulmonary macrophages according to different diseases. Referring to a lot of articles, the relationship between common diseases and macrophages was reviewed and the influencing factors in the particles uptake of alveolar macrophages were sum-marized. The review laid foundation for the development of preparations and clinical application of pulmonary drug delivery systems.