Application of serum IgG4 and IgE in children with allergic asthma and rhinallergosis
10.3969/j.issn.1673-4130.2017.04.004
- VernacularTitle:血清IgG4和IgE在儿童过敏性哮喘和过敏性鼻炎中的应用
- Author:
Xingxing LUO
;
Zhanze CHEN
;
Yangyang XU
;
Wenhua OU
;
Zhiguang MAI
;
Weixuan LI
- Keywords:
allergic asthma;
rhinallergosis;
children
- From:
International Journal of Laboratory Medicine
2017;38(4):442-443,446
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect serum IgG4 and IgE levels in children with allergic asthma and rhinallergosis to provide an im-portant laboratory evidence for its diagnosis ,treatment and prevention.Methods The serum IgG4 and IgE levels were detected in 118 children patients with allergic asthma ,167 children patients with rhinallergosis and 150 healthy children(control group) under-going physical examination in the same period.Results The levels of serum IgG4 and IgE in the allergic asthma group and rhinal-lergosis group were significantly higher than those in the control group ,the difference was statistically significant (P<0.05).In the intra-group comparison of the allergic asthma group and rhinallergosis group ,the positive rate of serum IgG4 was higher than that of serum IgE ,the difference was statistically significant (P<0.05).The positive rate of joint detection of serum IgG4 and IgE in these two groups was higher than that of single index detection ,the difference was statistically significant (P<0.05).The positive rate of serum IgG4 in the allergic asthma group was lower than that in the rhinallergosis group ,the difference was statistically sig-nificant(P<0.05).The positive rate of serum IgE in the allergic asthma group was lower than that in the rhinallergosis group ,but the difference was not statistically significant (P>0.05).Conclusion Serum IgG4 and IgE have a certain clinical significance in the occurrence ,treatment and surveillance of allergic asthma and rhinallergosis in children.
