Comparative study of hand-assisted laparoscopy and laparoscopy-assisted radical operation for colorectal cancer
10.7652/jdyxb201701019
- VernacularTitle:手辅助腹腔镜与腹腔镜辅助手术治疗结直肠癌的对比研究
- Author:
Xiongwei HUO
;
Xiaolong WANG
;
Guangbing WEI
;
Xuejun SUN
;
Yanfeng GAO
- Keywords:
colorectal cancer;
hand-assisted laparoscopic surgery;
treatment;
stress inflammatory factor;
clini-cal research
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2017;38(1):92-95,126
- CountryChina
- Language:Chinese
-
Abstract:
ABSTRACT:Objective To compare the short-term efficacy of hand-assisted laparoscopic surgery and laparoscopy-assisted radical operation,and evaluate the safety of hand-assisted laparoscopic surgery and its effect on systemic stress inflammation in colorectal cancer.Methods Totally 100 patients who had colorectal cancer and underwent radical operation from September 2012 to March 2016 were selected and divided into hand-assisted laparoscopy group (Group A,n=6 3 )and laparoscopy-assisted group (Group B,n=3 7 )according to the random number table.We compared operation index,postoperative complications and systemic inflammatory response levels in the two groups.Results Group B outperformed Group A in operation time,bleeding volume and drainage volume (P<0 .0 5 ),but with longer flatus time after operation than that in Group A (P<0 .0 5 ).There was no significant difference in hospitalization length and the incidence of postoperative complications between the two groups (P>0 .0 5 ).Systemic inflammatory reaction index of neutral granulocyte number and C reactive protein (CRP)showed no significant differences between the two groups (P>0 .0 5 ),but inflammatory cytokine IL-6 level in Group B was significantly higher than the that in Group A (P<0.05).Conclusion Hand-assisted laparoscopic surgery has shorter operation time,lower bleeding volume than laparoscopy-assisted operation in the treatment of colorectal cancer,but the latter one has more advantages in postoperative gastrointestinal function recovery.The inflammatory cytokine IL-6 level in hand-assisted laparoscopic surgery is higher than that in laparoscopy,suggesting that the choice of operation methods should be based on the actual situation in clinical application.
