Clinicopathological Characteristics of Primary Renal Mucosa Associated Lymphoid Tissue Lymphoma:A Case Report and Review Literature
10.3969/j.issn.1671-7414.2017.01.033
- VernacularTitle:肾原发性黏膜相关淋巴组织淋巴瘤一例临床病理特征及文献回顾
- Author:
Bingwei DONG
;
Wensheng LI
;
Xiaoyan MA
;
Yanhong SHI
;
Xining ZHU
- Keywords:
renal;
MALT lymphoma;
clinical pathological
- From:
Journal of Modern Laboratory Medicine
2017;32(1):121-123,127
- CountryChina
- Language:Chinese
-
Abstract:
Objective Primary renal mucosa associated lymphoid tissue lymphoma (MALT lymphoma)is very rare,here dis-cuss the clinical pathological characteristics and diagnosis,differential diagnosis of primary renal MALT lymphoma.Methods A case of primary renal MALT lymphoma was assayed for clinical and histopathological morphology,an well as immuno-histochemical staining,then reviewed the relevant literature.Results The clinical and imaging characteristics of renal lym-phoma lack of specific performance,the tissue section of the kidney biopsy showed diffuse infiltration of small lymphocytes. The small lymphocytes were centrocytes-like,monocytes-like,and plasma cell differentiation was recognized.Lymphoepithe-lial lesions were scattered.Follicular implanted phenomenon could been seen.Immunohistochemically result:the tumor cells were positive for CD20,PAX-5,CD79αand MUM-1,but negative for CD3,CD5,CD45RO,bcl-2,CD10,bcl-6 and CyclinD1. CD2 1 showed damage FDC network,positive for Kappa,negative for lambda,and it showed monoclonal phenotype,the Ki-6 7 index was about 35%.Final pathology diagnosis was primary renal MALT lymphoma.Conclusion Primary renal MALT lymphoma is very rare,the clinical manifestations and imaging characteristic of renal lymphoma are non-specific and misdiag-nosis frequently occurs in clinical practice,definite diagnosis depends on pathological examination,immunohistochemical stai-ning is helpful to differential diagnosis.
