Comparison of CRP,PCT and IL-6 in patients with two types of ends of HBV infection
10.3969/j.issn.1673-4130.2016.18.003
- VernacularTitle:两类 HBV 感染终末患者CRP、PCT 、IL-6水平及临床特征的比较
- Author:
Yu WANG
;
Longqin CHEN
;
Zihao ZHANG
;
Liyuan TIAN
- Publication Type:Journal Article
- Keywords:
C reactive prote;
interleukin-6;
procalcitonin;
HBV infection;
prognosis
- From:
International Journal of Laboratory Medicine
2016;37(18):2511-2512,2516
- CountryChina
- Language:Chinese
-
Abstract:
Objective We investigate the possible effect of inflammative indicator C reactive protein(CRP) ,interleukin‐6(IL‐6) and procalcitonin(PCT) on the outcome of HBV infection .Methods The clinical data and peripheral serum of 48 patients with HBV related hepatocellular carcinoma and 48 patients with decompensated cirrhosis were collected ,HBV copy numbers ,PCT ,IL‐6 , CRP ,ALT ,AST ,prothrombin time(PT ) and other indicators were tested for comparison and correlative analysis .Results HBV copy numbers ,PCT ,CRP ,lymphocytes and mononuclear cells showed no significant difference between primary hepatocellular car‐cinoma and decompensated cirrhosis group;however ,IL‐6 level was significantly higher in decompensated liver cirrhosis than in hep‐atocellular carcinoma ,as opposed to the absolute number of neutrophils .Conclusion IL‐6 increase may be related to final outcome of HBV infection ,dynamic monitoring IL‐6 is helpful to evaluate the prognosis of HBV infection .
