Clinical Observation of Zishen Jianpi Huoxue Decoction Combined with Xiaoxintong Capsule in the Treat-ment of Type 2 Diabetes Complicating with Silent Myocardial Ischemia
10.6039/j.issn.1001-0408.2016.17.34
- VernacularTitle:滋肾健脾活血汤联合消心痛胶囊治疗2型糖尿病合并无痛性心肌缺血的临床观察
- Author:
Lihua XIE
;
Hang ZHENG
- Publication Type:Journal Article
- Keywords:
Zishen jianpi huoxue decoction;
Xiaoxintong capsule;
Type 2 diabetes;
Silent myocardial ischemia
- From:
China Pharmacy
2016;27(17):2405-2406,2407
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe clinical efficacy and safety of Zishen jianpi huoxue decoction combined with Xiaoxintong capsule in the treatment of type 2 diabetes complicating with silent myocardial ischemia (SMI). METHODS:126 patients with type 2 diabetes complicating with SMI were selected and randomly divided into control group(62 case)and observation group(64 cases). Both group were given diet guidance and hypoglycemic drugs as sulfonylureas,biguanides. Control group was given Xiaox-intong capsule 10 mg,tid;observation group was additionally given Zishen jianpi huoxue decoction 400-500 ml,bid. Both groups received treatment for 7 d. Therapeutic efficacy of thoracic obstruction,improvement of coronary artery branch stenosis and times and duration of electrocardiogram ST segment low voltage outlet were observed in 2 groups. ADR was compared between 2 groups. RESULTS:Therapeutic efficacy of thoracic obstruction and improvement of coronary artery branch stenosis in observation group were significantly better than in control group,with statistical significance(P<0.05);the times and duration of electrocardiogram ST segment low voltage outlet in observation group were significantly lesser shorter than in control group,with statistical signifi-cance (P<0.05). No obvious ADR was found in 2 groups. CONCLUSIONS:Zishen jianpi huoxue decoction complicating with Xiaoxintong capsule shows significantly therapeutic efficacy in the treatment of type 2 diabetes complicating with SMI with good safety.
