The Clinicopathological Features of Gastric Hyperplastic Polyps with Neoplastic Transformations: A Suggestion of Indication for Endoscopic Polypectomy.
- Author:
A Reum HAN
1
;
Chang Ohk SUNG
;
Kyoung Mee KIM
;
Cheol Keun PARK
;
Byung Hoon MIN
;
Jun Haeng LEE
;
Jin Yong KIM
;
Dong Kyung CHANG
;
Young Ho KIM
;
Poong Lyul RHEE
;
Jong Chul RHEE
;
Jae J KIM
Author Information
1. Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. jjkim@skku.edu
- Publication Type:Original Article
- Keywords:
Hyperplastic polyp;
Neoplastic transformation;
Endoscopic polypectomy
- MeSH:
Biopsy;
Humans;
Polyps;
Surgical Instruments
- From:Gut and Liver
2009;3(4):271-275
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND/AIMS: Although gastric hyperplastic polyps are usually considered as benign lesions, a low risk of carcinomatous conversion is currently recognized. We aimed to identify the characteristics of hyperplastic polyps undergoing neoplastic transformation. METHODS: A total of 269 gastric hyperplastic polyps from 216 patients removed by endoscopic polypectomy (EP) or surgical resection were enrolled in this study, and their endoscopic pictures and pathology slides were reviewed. RESULTS: Neoplastic transformation was detected on forceps biopsy specimen in 11 cases. However, the pathology findings from the EP or surgical specimen revealed neoplastic transformation in 14 cases (5.2%; 4 with dysplasia and 10 with adenocarcinoma). No significant difference was found between hyperplastic polyps with and without neoplastic transformation in age, sex, location, number of polyps or gross appearance. However, neoplastic transformations were more frequently found in gastric hyperplastic polyps >1 cm than in polyps < or =1 cm (12 of 143; 8.4% vs. 2 of 126; 1.6%) (p=0.013). CONCLUSIONS: Neoplastic transformations were more frequently found in gastric hyperplastic polyps >1 cm. Therefore, EP should be considered for gastric hyperplastic polyps >1 cm for the accurate diagnosis and definitive treatment.
