Improvement of Quality Standard for Lanqiao Jiedu Oral Liquid
- VernacularTitle:蓝翘解毒口服液的质量标准的提高
- Author:
Chun TAO
;
Danping XUE
;
Aiwen HUANG
;
Hongtao SONG
- Publication Type:Journal Article
- Keywords:
Lanqiao Jiedu oral liquid;
Quality standard;
TLC;
HPLC
- From:
China Pharmacist
2016;19(9):1763-1765,1766
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish and improve the quality standard for Lanqiao Jiedu oral liquid. Methods:A TLC was used for the qualitative identification of Forsythiae Fructus, Sophorae Tonkinensis Radix Et Rhizoma and Anemarrhenae Rhizoma. An HPLC was used for the qualitative identification of Isatidis Radix. Forsythin in Forsythiae Fructus was quantitatively identified by HPLC. Results:Forsythiae Fructus, Sophorae Tonkinensis Radix Et Rhizoma and Anemarrhenae Rhizoma showed clear spots and there was no interfer-ence from the negative control. The HPLC further confirmed Isatidis Radix was ( R, S)- epigoitrin. Quantitative study of forsythin re-vealed good specificity without interference from the negative control. Conclusion: The study provides an improved quality standard with high specificity and reproducibility, which can be applied in the quality control of Lanqiao Jiedu oral liquid.
