Quality Standard for Biyankang Granule
- VernacularTitle:鼻炎康颗粒质量标准的建立
- Author:
Peipei CAI
;
Xiaodan ZHANG
- Publication Type:Journal Article
- Keywords:
Biyankang granule;
Puerariae Iobatae radix;
Scutellaria baicalensis Georgi;
Baicalin;
Quality standard;
TLC;
HPLC
- From:
China Pharmacist
2016;19(9):1788-1790,1791
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish a method for the quality standard of Biyankang granule. Methods: Scutellaria baicalensis Georgi and Puerariae Iobatae radix were identified by TLC. The content of baicalin was determined by HPLC with a Dubhe C18 column (250 mm × 4. 6 mm, 5 mm). The mobile phase was methanol and 0. 4% phosphoric acid with gradient elution. The flow rate was 1. 0 ml· min-1 and the detection wavelength was 280 nm. The column temperature was 30℃ and the injection volume was 10 ml. Re-sults:The spots in TLC were clear without any interference. A good linear relationship was shown within the range of 15. 02-300. 43 m g·ml-1 for baicalin (r=1.000 0). The average recovery of baicalin was 102.62% (RSD =0.72%, n =6). Conclusion: The method is specific with high accuracy and good reproducibility, which can be used for the quality control of Biyankang granule.
