Analysis of Influential Factors of ADR Occurred in Patients of Geriatrics Department in Our Hospital
10.6039/j.issn.1001-0408.2016.20.14
- VernacularTitle:我院老年科患者药品不良反应发生的影响因素分析
- Author:
Hongying ZHAO
;
Guotao YANG
;
Haibin WANG
;
Huifang ZHANG
;
Wenhao WANG
;
Jingrui QI
- Publication Type:Journal Article
- Keywords:
Elderly patients;
ADR;
Influential factors
- From:
China Pharmacy
2016;27(20):2781-2782,2783
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the influential factors of adverse drug reaction(ADR)in elderly patients during medi-cation,and to provide reference for reducing the incidence of ADR in geriatrics department. METHODS:The clinical data of elder-ly patients admitted to our hospital from Jan. 2011 to Dec. 2015 were collected and analyzed by single factor and unconditional Loigstic multiple regression analysis. The risk influential factors of ADR were investigated. RESULTS:A total of 1 680 patients re-ceived drug therapy,and the incidence of ADR was 7.92%(133/1 680). Organs/systems involved in ADR were mainly allergic re-action(49 cases,36.84%)and digestive system(48 cases,36.09%). The results of single factor analysis showed that the age of patients,drug dosage,route of administration,treatment course,the type numbers of drug combination and others were the inde-pendent influential factors of ADR. By unconditional Loigstic multiple regression analysis,it was found that the risk of ADR in-creased with the drug dosage,treatment course,intraverous administration and various drugs use,etc. CONCLUSIONS:It is nec-essary to pay attention to ADR monitoring,particularly risk factors monitoring of ADR in the elderly patients,strengthen medica-tion guidance to improve medication compliance,take the necessary preventive measures to reduce the incidence of ADR.
