Population analysis of clinical Vibrio parahaemolyticus strains from Asia based on multilocus sequence typing and AA-multilocus sequence typing
10.7644/j.issn.1674-9960.2016.09.007
- VernacularTitle:亚洲副溶血弧菌临床菌株的基于碱基序列和肽链序列的多位点序列分型研究
- Author:
Jialiang XU
;
Xiaoli DU
;
Junhan LIU
;
Biao KAN
;
Xin LU
- Publication Type:Journal Article
- Keywords:
Vibrio parahaemolyticus;
multilocus sequence typing;
peptide based multilocus sequence typing;
clonal complex
- From:
Military Medical Sciences
2016;40(9):722-724,745
- CountryChina
- Language:Chinese
-
Abstract:
Objective To find out more about the population structure and clonal complex of clinical Vibrio parahaemolyticus strains in Asia.Methods Clinical Vibrio parahaemolyticus strains data were screened in Asia with complete ST and pST types from PubMLST public database,their subgroup and complex were analyzed,and the minimum spanning tree based on ST and pST types respectively was completed.Results From the database,341 items of ST and pST types of Asian clinical Vibrio parahaemolyticus strains were screened,including 157 ST,most of which were of ST3 type.Totally 214 items of data came from China (including Hong Kong and Taiwan),and covered 133 ST,most of which were of ST3 type.eBURST software was used and 17 groups and 94 singletons were found.Software STRUCTURE analysis showed that the appropriate subset number of clinical V.parahaemolyticus strains in Asia was 7,and that the average distance between samples in each subgroup was 0.9113.Conclusion Clinical V.parahaemolyticus strains in Asia show high diversity and can be subdivided into seven subgroups.ST3 type is dominating when multilocus sequence typing(MLST)is used and pST2 type is the majority by AA-MLST typing.
