Value of high-sensitive troponin I detection in the diagnosis of early myocardial injury
10.3969/j.issn.1673-4130.2016.19.004
- VernacularTitle:超敏肌钙蛋白I检测在糖尿病心肌损伤早期诊断中的价值
- Author:
Chao QIAN
;
Feifei GU
;
Yingying DING
;
Jianhua YU
;
Tian CHEN
- Publication Type:Journal Article
- Keywords:
high-sensitive troponin I;
type 2 diabetes mellitus;
myocardial injury;
HbA1c
- From:
International Journal of Laboratory Medicine
2016;37(19):2670-2671,2674
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of high‐sensitive troponin I detection in the diagnosis of early myocardial inju‐ry .Methods Totally 240 type 2 diabetes mellitus (T2DM ) patients (study group) and 40 healthy people(healthy control group) were chosen as subjects .The serum level of HbA1c ,AST ,CK ,CK‐MB and hs‐cTnI were measured among the two groups ,respec‐tively .Results Hs‐cTnI level in T2DM group was significantly higher than in healthy control group(P< 0 .05) ,and AST ,CK and CK‐MB levels in two groups had no significant difference(P> 0 .05) .Hs‐cTnI level and positive rate in HbA1c ≥ 6 .5% group was significantly higher than in HbA1c ≤ 6 .4% group(P< 0 .05) ,and no significant difference of AST ,CK and CK‐MB levels and posi‐tive rate were observed in two groups(P> 0 .05) .There was a positive correlation between the level of HbA1c and that of serum hs‐cTnI in T2DM group(r= 0 .471 ,P< 0 .05) .Conclusion The hs‐cTnI level detection has important clinical value in the diagnosis of early myocardial injury in T2DM patients ,and HbA1c is positively correlated with hs‐cTnI .
