Measurement Uncertainty in the Content Determination of Paracetamol Tablets by UV
- VernacularTitle:紫外分光光度法测定对乙酰氨基酚片含量的测量不确定度评估
- Author:
Yi ZUO
;
Luhua FEI
- Publication Type:Journal Article
- Keywords:
Paracetamol tablets;
Determination;
UV;
Uncertainty assessment
- From:
China Pharmacist
2016;19(10):2005-2006,2007
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the measurement uncertainty in the determination of paracetamol tablets by UV. Methods:The mathematical model of content determination by UV was established and the uncertainty sources were analyzed. Each active component of uncertainty was calculated, and the expanded uncertainty was obtained. Results:The expanded uncertainty for the UV determination of paracetamol tablets was 1. 2%,and the content determination result was (97. 0 ± 1. 2) % (k=2). Conclusion:The main sources of uncertainty are analyzed, which can provide reliable theoretical basis for the effective control of the method.
