Research progress of anti-osteoporotic effects of genistein
10.3969/j.issn.1001-1978.2016.10.004
- VernacularTitle:染料木素抗骨质疏松研究进展
- Author:
Wenxiu LAI
;
Yajun YANG
;
Liao CUI
- Publication Type:Journal Article
- Keywords:
genistein;
osteoporosis;
osteoblast;
osteoclast;
phy-toestrogens;
mechanism
- From:
Chinese Pharmacological Bulletin
2016;32(10):1345-1347,1348
- CountryChina
- Language:Chinese
-
Abstract:
Genistein, as one kind of phytoestrogens, can stimu-late osteoblastic proliferation, differention and mineralization, and can also inhibit bone resorption activity of osteoclast. The effect of genistein on bone metabolism lies in various molecular mechanisms. This paper reviews the research progress of the an-ti-osteoporotic action of genistein and its mechanism, which may provide a basis for the research and development of new agents to treat osteoporosis.