Effect of laparoscopic-assisted radical resection on HO-1 and YKL-40 in patients with rectal cancer﹡
10.3969/j.issn.1671-8348.2016.30.014
- VernacularTitle:腹腔镜辅助直肠癌根治术对患者血清中 HO-1及 YKL-40的影响
- Author:
Zhongyuan LIU
;
Wen ZHAO
;
Li ZHANG
- Publication Type:Journal Article
- Keywords:
rectal cancer;
heme oxygenase-1;
chitinase-3-1ike protein 1
- From:
Chongqing Medicine
2016;45(30):4220-4221,4225
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the changes of serum levels of heme oxygenase‐1(HO‐1) ,C‐reactive protein(CRP) and Chitinase‐3‐1ike protein 1(YKL‐40) in patients with rectal cancer after laparoscopic‐assisted radical operation versus open radical surgery .Methods According the integration and elimination standard ,60 cases of patients with rectal cancer were selected and di‐vided into laparoscopic group (30 cases) and open group (30 cases) ,the concentrations of HO‐1 ,YKL‐40 and CRP in peripheral blood of patients were detected on the first and third postoperative day and preoperative day(P<0 .05) ,and were compared between the two groups .Results The serum levels of HO‐1 ,YKL‐40 and CRP in the laparoscopic group were significantly lower than those in the open group on the first and third postoperative day(P<0 .05) .The serum levels of HO‐1 ,YKL‐40 and CRP were significant‐ly increased after surgery ,and serum levels of HO‐1 and CRP on third postoperative day were significantly increased compared with that on the first postoperative day in the two groups after surgery ,while serum level of YKL‐40 on the third postoperative day was significantly lower than that on the first postoperative day in the two groups after surgery .Conclusion The stress reaction is com‐paratively mild in patients with rectal cancer after laparoscopic assisted radical operation ,and the postoperative period may be shor‐ter in patients treated with laparoscopic assisted radical operation than those treated with open radical surgery .
