Clinical Utilization Investigation and Rationality Analysis of Carbapenems in A Hospital
10.6039/j.issn.1001-0408.2016.29.04
- VernacularTitle:某院碳青霉烯类抗菌药物的临床应用调查与用药合理性评估
- Author:
Nan ZHANG
;
Hongliu LU
;
Huijuan YANG
;
Taoyuan LI
;
Wenbin XIA
- Publication Type:Journal Article
- Keywords:
Carbapenems;
Antibiotics;
Prescription evaluation;
Rational drug use
- From:
China Pharmacy
2016;27(29):4047-4049,4050
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the clinical utilization of carbapenems in a hospital,analyze and evaluate its medication rationality. METHODS:All the 508 medical records of inpatients treated with carbapenems from Jul. 2012 to Jun. 2015 were retro-spectively investigated,the utilization and pathogenic examination of carbapenems were evaluated;by setting the carbapenems eval-uating standard,the medication rationality of carbapenems was evaluated and inappropriate cases were classified and analyzed statis-tically. RESULTS:The drug utilization indexed (DUI) of Imipenem and cilastatin sodium for injection and Meropenem for injec-tion were 0.80 and 1.32,respectively;the total rate of microbial inspection was 95.9%;according to the drug sensitive test result, the rate of drug selection was 62.8%;there were 54 cases(10.6%)of irrational use records,in which,irrational dosage(42.6%) and improper drug selection (31.4%) were the major problems. CONCLUSIONS:There are some inappropriate medication prob-lems in carbapenems utilization in the hospital. Developing the carbapenems utilization evaluation is helpful to discover typical medi-cation problems,which can provide reference for intervention and continuous improvement of rational drug use.
