Analysis of Quinolones-induced ADR Reports in Our Hospital from 2011 to 2014

VernacularTitle:我院2011－2014年喹诺酮类药物致不良反应报告分析
Author: Peipei REN
Publication Type:Journal Article
Keywords: Quinolones; Adverse drug reaction; DDDs; Report; Analysis
From: China Pharmacy 2016;27(29):4083-4084,4085
CountryChina
Language:Chinese
Abstract: OBJECTIVE:To investigate the general regularity and characteristics of ADR induced by quinolones,and to pro-vide reference for rational drug use in the clinic. METHODS:A total of 84 quinolones-induced ADR reports in our hospital from 2011 to 2014 were analyzed statistically in respects of general information,drug use,organs/systems involved in ADR,clinical manifestations,outcome and DDDs. RESULTS:The adverse reactions were caused by 7 kinds of drugs,among which 89.29% of them were caused by intravenous injections,manifesting as lesion of skin and its appendants,digestive system and nervous system injury,etc. The proportion of female patients(60.71%)was higher than that of male(39.29%). No serious ADR was found,and all patients were recovered or cured. CONCLUSIONS:Gatifloxacin injection shows the low safety. The monitoring of ADR in-duced by quinolones should be strengthened to ensure the safe and effective use of drugs.