Pharmaceutical Care for A Patient with Hemodialysis Complicated with Subacute Infective Endocarditis
10.6039/j.issn.1001-0408.2016.29.39
- VernacularTitle:血液透析伴亚急性感染性心内膜炎患者的药学监护
- Author:
Zhen LIU
;
Xingyun HOU
;
Yunlei YUN
;
Wansheng CHEN
- Publication Type:Journal Article
- Keywords:
Subacute infective endocarditis;
Hemodialysis;
Clinical pharmacists;
Pharmaceutical care
- From:
China Pharmacy
2016;27(29):4150-4151,4152
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the role of clinical pharmacists providing pharmaceutical care for hemodialysis patients complicated with subacute infective endocarditis(IE). METHODS:Clinical pharmacists participated in the anti-infection treatment for a hemodialysis patients complicated with subacute IE,according to the antimicrobial spectrum,laboratory and imaging find-ings,and patient’s condition changes,assisted physician to optimize the regimen,clinical pharmacists suggested to give imipenem cilastatin sodium after hemodialysis,adjust the initial dose of teicoplanin and give 1 g vancomycin firstly,and maintained 0.5 g af-ter hemodialysis,then adjust its dose based on blood plasma concentration;during treatment,clinical pharmacists closely observed the treatment effect and adverse reactions,providing blood plasma concentration monitoring,medication reminding and medication education. RESULTS:Physicians adopted parts of suggestions of clinical pharmacists,no fever was found,hemogram returned to normal,no abnormal echocardiography,and patient discharged. CONCLUSIONS:Clinical pharmacists guarantee the safety and ef-ficacy of drug use by adopting dose of anti-infection drugs,evaluating efficacy,monitoring adverse reactions and vancomycin plas-ma concentration,and assisting physicians to optimize treatment regimen.