Pharmaceutical Care for Allergic Shock Induced by Heamocoagulase Agkistrodon for Injection
10.6039/j.issn.1001-0408.2016.29.40
- VernacularTitle:注射用尖吻蝮蛇血凝酶致过敏性休克的药学监护
- Author:
Liyun WANG
;
Lei GONG
;
Jilan ZHAO
- Publication Type:Journal Article
- Keywords:
Heamocoagulase agkistrodon for injection;
Allergic shock;
Pharmaceutical care
- From:
China Pharmacy
2016;27(29):4152-4154,4155
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To guide rational use of Heamocoagulase agkistrodon for injection,and to provide reference for phar-maceutical care. METHODS:Treatment methods and outcome of 9 cases of allergic shock induced by Heamocoagulase agkistrodon for injection were retrieved from CNKI and VIP database during 2009-2015,and then analyzed statistically,based on one case of allergic shock induced by Heamocoagulase agkistrodon for injection in the Affiliated Hospital of Zhunyi Medical College. RE-SULTS:10 pationts with allergic shock induced by Heamocoagulase agkistrodon for injection mainly used the drug for hemostasis before and after surgery,heavy menstrual bleeding,etc.,with dose of 1 or 2 U. Route of administration included intravenous injec-tion and intravenous dripping. Allergic shock often occurred within 30 min after medication. CONCLUSIONS:The use of Heamoco-agulase agkistrodon for injection in some patients belongs to off-label drug use,and route of administration is different from that stated in package inserts. Allergic shock induced by Heamocoagulase agkistrodon for injection occurs rapidly;the drug should be used strictly according to package inserts and authoritative literatures;emergency plan should be developed before medication in or-der to guarantee the safety of drug use.
