Detection and Clinic Application of Antiphospholipid Antibody and Anti-β2-GPⅠ in Female Infertility
10.3969/j.issn.1671-7414.2016.05.042
- VernacularTitle:女性不孕症患者抗心磷脂抗体和抗β2-糖蛋白1抗体的检测及临床应用
- Author:
Jie HUANG
;
Qing WANG
;
Liangjun LI
;
Ce ZHANG
- Publication Type:Journal Article
- Keywords:
anti cardiolipin antibody;
anti-betaβ2-Glycoprotein Ⅰ antibody;
female infertility
- From:
Journal of Modern Laboratory Medicine
2016;31(5):142-143,146
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the correlation of different antiphospholipid antibody isotypes in female infertility.Methods Selected 296 patients with female infertility and 31 normal female between May 2015 to August 2015 in Dalian Women’s and Children’s Medical Centre.All the antibodies were detected by chemilumininescence.The positiverate of antipholipid an-tibodies in female infertility patients and health controls were calculated.The concentrations of antiphospholipid antibodies in different groups were compared with Mann-Whitney U test.Results The positive rate of aCL IgG of female infertility and normal female were 0.34% and 0.00%.The positive rate of aCL IgM of female infertility and normal female were 1.35%and 0.00%.The positive rate ofβ2 GPⅠ IgG of female infertility and normal female were 0.00% and 0.00%.The positive rate ofβ2 GPⅠ IgM of female infertility and normal female were 0.34% and 0.00%.aCL IgG were differet beween female infertility and normal female (P=0.013),others had on significant difference.Conclusion Need to detect LA,combined with aCL and anti-β2 GPⅠ,exclusively diagnose APS,layed the foundation of sequential treatment.
