Studies About the Relationship between miR-1 2 2 and Hepatitis C Virus and Hepatocellular Carcinoma
10.3969/j.issn.1671-7414.2016.05.047
- VernacularTitle:miRNA-122与丙肝病毒感染及肝癌关系的研究进展
- Author:
Fangping WANG
;
Pingan ZHANG
;
Zhili NIU
- Publication Type:Journal Article
- Keywords:
miR-122;
hepatitis C virus;
hepatocellular carcinoma
- From:
Journal of Modern Laboratory Medicine
2016;31(5):157-159,164
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis C virus (HCV)was easily developed into hepatitis,cirrhosis and liver cancer after infecting human.Cur-rently,the traditional method of treatment of HCV was pegylated interferon and ribavirin program,which was ineffective and had poor side effects,while the new direct antiviral drugs were expensive.Therefore,looking for cheap and non-toxic side effects of treatment was the focus of current research.More and more evidence indicate that micro-Ribose Nucleic Acid (miRNAs)play an important role in the development of liver disease,regeneration and functional regulation.This review studies the relationship between miR-122 and Hepatitis C virus and hepatocellular carcinoma.