Cost-effectiveness Analysis of 3 Kinds of Statins in the Treatment of Hyperlipidemia

VernacularTitle:3种不同他汀类药物治疗高脂血症的成本-效果分析
Author: Rong BAI
Publication Type:Journal Article
Keywords: Statins; Hyperlipidemia; Pharmacoeconomics; Cost-effectiveness analysis; Simvastatin
From: China Pharmacy 2015;(26):3620-3621,3622
CountryChina
Language:Chinese
Abstract: OBJECTIVE:To compare cost-effectiveness of 3 kinds of statins in the treatment of hyperlipidemia. METHODS:180 hyperlipidemia patients were randomly divided into 3 group,with 60 cases in each group. Group A was given Atorvastatin tablet 20 mg/time,once a day;group B received Simvastatin tablet 20 mg/time,once a day;group C was given Rosuvastatin tablet 10 mg/time,once a day. Therapeutic efficacy was evaluated in 3 groups,and cost-effectiveness analysis was conducted. RESULTS:The ef-fective rate was 85.0% in group A,83.3% in group B and 81.7% in group C,there was no statistical significance(P>0.05). Total cost of 3 groups were 610.40 yuan,193.60 yuan and 408.00 yuan;the cost-effectiveness ratio of group B was 2.32,which was sig-nificantly lower than 7.18 of group A and 4.99 of group C,with statistical significance(P<0.05). The results of sensitivity analysis was consistent with it. CONCLUSIONS:Simvastatin is effective and economical medication in the treatment of hyperlipidemia.