Analysis of 111 Cases of Antibiotics-induced ADR Reports in Our Hospital

VernacularTitle:我院抗菌药物致不良反应111例分析
Author: Zhengze SHEN ; Chuan FU ; Mei JIN
Publication Type:Journal Article
Keywords: Antibiotics; ADR; Prevention countermeasures
From: China Pharmacy 2015;(26):3667-3668,3669
CountryChina
Language:Chinese
Abstract: OBJECTIVE:To investigate the characteristics and regulation of antibiotics-induced ADR in our hospital and ex-plore effective prevention measures,in order to provide reference for safe and rational use of antibiotics in the clinic. METHODS:111 antiobiotics-induced ADR reports were collected from our hospital during 2012-2014,and analyzed in terms of patient’s gender and age,route of administration,drug category,organs/systems involved in ADR,etc. RESULTS:The patients aged <10 years old and >60 years old took up the highest proportion,accounting for 27.93% and 25.23%,espectively. ADR induced by intrave-nous route of administration had the highest incidence,accounting for 84.68%;cephalosporins-induced ADR was the most,account-ing for 26.13%;lesion of skin and its appendents was main antibiotics-induced ADR,accounting for 44.92%. CONCLUSIONS:Clinical pharmacists should provide technical support to doctors and nurses to aviod the occurrence of ADR.