Study on the Quality Standard of Xianrengu Oral Liquid
10.6039/j.issn.1001-0408.2015.27.40
- VernacularTitle:仙人菇口服液的质量标准研究
- Author:
Jiamei LE
;
Xiaojuan XIONG
;
Wenquan LU
;
Shujuan PIAO
;
Feng ZHANG
- Publication Type:Journal Article
- Keywords:
Xianrengu oral liquid;
Quality standard;
TLC;
RP-HPLC;
Icariin
- From:
China Pharmacy
2015;(27):3855-3858,3859
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish the quality standard for Xianrengu oral liquid. METHODS:Thin layer chromatography (TLC) was used for qualitative identification of Epimedii Folium,Astragali Radix,lycium barbarum,Atractylodes macrocephala and Panax ginseng in Xianrengu oral liquid;RP-HPLC was preformed on the column of Dikma Diamonsil C18 with the mobile phase of acetonitrile-0.1% phosphoric acid (30∶70,V/V)at the flow rate of 1.0 ml/min,the detection wavelength was 270 nm,the temperature was 30℃and the volume was 10μl. RESULTS:TLC identification had good separation,clear spots and high specifica-tion. The linear range of icariin was 7.97-510.00 μg/ml(r=0.999 3);RSDs of precision,stability and reproducibility tests were no more than 0.83%;and the average recovery was 97.69%(RSD=1.30%,n=6). CONCLUSIONS:This method is simple,accu-rate and simple,which can be used for the quality control of Xianrengu oral liquid.
