Value of combined detection of serum BNP and TnI in patients with acute heart failure

VernacularTitle:血清BNP、TnI水平联合检测在急性心力衰竭患者诊治中的有效性评价
Author: Jinlong WANG ; Peisheng JIN
Publication Type:Journal Article
Keywords: BNP; TnI; acute heart failure
From: Chinese Journal of Biochemical Pharmaceutics 2016;36(9):144-145,148
CountryChina
Language:Chinese
Abstract: Objective To observe and explore the value of combined detection of serum BNP and TnI in patients with acute heart failure(AHF). Methods 60 AHF patients from February 2015 to April 2016 were selected as observation group, and divided into Level III group(n=32) and Level IV group(n=28) according to NYHA classification;60 healthy patients at the same period were selected as control group.BNP and TnI levels were detected by chemiluminescence in each group, and were compared.Results BNP and TnI of observation group were(2624.4 ±378.6) ng/mL and(0.87 ± 0.22) ng/mL, while in control group were(72.4 ±20.2) ng/mL and(0.13 ±0.02) ng/mL, the differences were significant(P<0.05);BNP and TnI in level III group before treatment were significantly lower than grade IV group(P<0.05), after treatment, the level of BNP and III in group IV and group TnI were significantly lower(P<0.05), and the levels of BNP and TnI were significantly lower than those in III group after treatment(P<0.05). Conclusion BNP combine with TnI levels monitoring play an important role in AHF diagnosis and prognosis evaluation, can help to guide the treatment of AHF.