The research progress of quassinoids components in Brucea javanica and their pharmacological activities
10.3969/j.issn.1001-1978.2016.11.001
- VernacularTitle:鸦胆子苦木内酯类成分及其药理活性研究进展
- Author:
Lixia FU
;
Chonggang HUANG
;
Mingbao LIN
;
Qi HOU
- Publication Type:Journal Article
- Keywords:
Brucea javanica L. Merr;
quassinoids;
pharmacolog-ical activities;
anti-tumor;
anti-inflammation;
research progress
- From:
Chinese Pharmacological Bulletin
2016;32(11):1481-1485,1486
- CountryChina
- Language:Chinese
-
Abstract:
Fructus Bruceae, the dry and ripe fruits of Brucea ja-vanica( L. ) Merr. ( Simaroubaceae) , has been used for dysenter-y, tumor, malaria and furunculosis treatment, and topical appli-cation for warts and corns. Quassinoids are the main chemical constituents of Fructus Bruceae, which have been proved to have anti-tumor, anti-inflammatory, insecticidal, anti-viral, anti-bac-terial and hypoglycemic activities, and so on. In view of the ex-tensive pharmacological activities of Fructus Bruceae, and better development and utilization of its medicinal value, the advances of quassinoids in Fructus Bruceae and their pharmacological ac-tivities are reviewed in this paper.