Effect of asymptomatic hyperuricemia on the postoperative functional recovery in patients with knee joint re-placement
10.11659/jjssx.02E016045
- VernacularTitle:无症状高尿酸血症对患者膝关节置换术后功能恢复的影响
- Author:
Zhikui YANG
;
Jianan DAI
;
Xi CAO
;
Yonggang LI
;
Peng LI
;
Xin GAO
;
Chong LIU
- Publication Type:Journal Article
- Keywords:
uric acid;
knee joint replacement;
osteoarthritis;
WOMAC
- From:
Journal of Regional Anatomy and Operative Surgery
2016;25(11):834-836,837
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of asymptomatic hyperuricemia on the postoperative functional recovery in osteoarthritis (OA)patients with knee joint replacement.Methods Among the 294 patients who recieved knee joint replacement in our hospital from Feb-ruary 2013 to September 2015,a total of 187 patients were included in this study with 79 cases in the hyperuricemia group and the other 108 cases in the control group.The WOMAC index of the two groups were analyzed before the surgery,2 weeks,3 months,and 6 months after the knee joint replacement surgery.Multivariable linear regression was performed to test the effect of impact factors on the variation of WOMAC index.Results The WOMAC index of the two groups significantly increased 2 weeks after surgery,and the difference was statistically signifi-cant(P <0.05).And the WOMAC index of the control group was higher than that in the hyperuricemia group 2 weeks and 3 months after sur-gery with statistically significant difference(P <0.05).Conclusion The uric acid level before surgery was a influence factor of WOMAC index, and high uric acid level before knee joint replacement has negatively impact for the postoperative functional recovery in the osteoarthritis patients.
