Literature Analysis of 284 Cases of ADR/ADE Induced by Glycerol Fructose Injection

VernacularTitle:284例甘油果糖注射液致不良反应/不良事件报告分析
Author: Wenwu LI ; Li WANG
Publication Type:Journal Article
Keywords: Glycerol fructose injection; Adverse drug reaction/adverse drug event; Instruction; Analysis
From: China Pharmacy 2015;(30):4226-4227,4228
CountryChina
Language:Chinese
Abstract: OBJECTIVE:To explore the general rules and characteristics of ADR/ADE induced by Glycerol fructose injection and provide reference for clinical ration drug use. METHODS:284 cases of ADR/ADE induced by Glycerol fructose injection from Jan. 2004 to Oct. 2014 in Drug ADR Monitoring Center of Henan Province were statistically analyzed and comparatively analyzed with the drug instructions in 11 domestic drug manufacturing enterprises. RESULTS:ADR/ADE induced by Glycerol fructose injec-tion was related to gender,mainly adult male,and ADR/ADE might occurred within 30 min;main clinical manifestations were skin and its appendages damages,medication site damage and systemic damage. There were larger differences among the notes de-scription in the package inserts from 11 drug manufact urers. CONCLUSIONS:The clinic should strengthen the monitoring of ADR/ADE induced by Glycerol fructose injection,try to avoid or reduce the incidence of ADR,improve the drug instructions and ensure medication safety.