Efficacy and Safety Observation of Ferrous Succinate in the Treatment of Pregnancy Complicated with Iron Deficiency Anemia
10.6039/j.issn.1001-0408.2015.24.09
- VernacularTitle:琥珀酸亚铁治疗妊娠合并缺铁性贫血的疗效与安全性观察
- Author:
Feihong ZHANG
;
Junhua HU
- Publication Type:Journal Article
- Keywords:
Ferrous succinate;
Pregnancy;
Iron deficiency anemia;
Efficacy;
Safety
- From:
China Pharmacy
2015;(24):3335-3336,3337
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the efficacy and safety of ferrous succinate in the treatment of pregnancy complicated with iron deficiency anemia. METHODS:90 pregnant women with iron deficiency anemia were randomly divided into treatment group and control group. All patients were stopped drugs related to iron supplement 2 weeks before treatment,and the blood index-es were detected,including red blood cell count (RBC),hemoglobin concentration (Hb) and serum ferritin concentration (SF), etc. The treatment group was orally given 2 Ferrous succinate tablets after a meal,twice a day;control group was orally given 2 Ferrous sulfate tablets after a meal,twice a day. The treatment course for both groups was 1 month. The clinic data was observed, including clinical efficacy,RBC,Hb and SF level before and after treatment,and the incidence of adverse reactions. RESULTS:The total effective rate in treatment group was significantly higher than control group,the difference was statistically significant(P<0.05). After treatment,the RBC,Hb and SF level in 2 groups were significantly higher than before,and treatment group was high-er than control group,the differences were statistically significant(P<0.05). The difference was not statistically significant in the in-cidence of adverse reactions(P>0.05). CONCLUSIONS:Ferrous succinate tablets has good efficacy and safety in the treatment of pregnancy complicated with iron deficiency anemia.
