Observation and Nursing of Hemorrhage Complications in Alteplase Intravenous Thrombolysis
10.6039/j.issn.1001-0408.2015.23.22
- VernacularTitle:阿替普酶静脉溶栓治疗中出血性并发症的观察及护理
- Author:
Liping LIANG
;
Hua HUANG
- Publication Type:Journal Article
- Keywords:
Alteplase;
Intravenous thrombolysis;
Hemorrhage
- From:
China Pharmacy
2015;(23):3236-3237,3238
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the observation and nursing points of hemorrhage in intravenous thrombolysis after using alteplase. METHODS:128 patients underwent alteplase intravenous thrombolysis were selected as the research object. The occur-rence of hemorrhage in each part were observed within 48 hours after medication and nursed timely. RESULTS:128 patients re-ceived intravenous thrombolysis. 48 h later,26 patients suffered from hemorrhage complications (20.3%). Among them,there were 6 cases of nose bleeding (4.7%),8 cases of subcutaneous congestion (6.3%),6 cases of gingival bleeding (4.7%) and 6 cases of gastrointestinal bleeding(4.7%). There was no significant difference in the incidence of complications among those groups (P>0.05). The time of nose bleeding was (3.2 ± 1.3) h,the time of subcutaneous congestion (3.5 ± 1.2)h,the time of gingival bleeding(1.5±0.7)h,and the time of gastrointestinal bleeding(4.1±1.8)h. The time of gingival bleeding was earlier than that of other groups,with statistically significant difference(P<0.05). There was no statistically significant difference among other groups (P>0.05). CONCLUSIONS:In alteplase intravenous thrombolysis,nurses should closely monitor hemorrhage and complications, especially the complication of gingival bleeding. Find out the complications timely and nurse it as early as possible.
