Clinical Observation of Houttuynia cordata Eye Drops Combined with Olopatadine Eye Drops in the Treat-ment of Allergic Conjunctivitis
10.6039/j.issn.1001-0408.2015.23.31
- VernacularTitle:鱼腥草滴眼液联合奥洛他定滴眼液治疗过敏性结膜炎的临床观察
- Author:
Yan HUANG
;
Zhongpei CHEN
;
Weimin CHEN
;
Zhu SHOU
;
Sufen PENG
- Publication Type:Journal Article
- Keywords:
Houttuynia cordata eye drops;
Olopatadine eye drops;
Allergic conjunctivitis;
Drug combination
- From:
China Pharmacy
2015;(23):3261-3262,3263
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe clinical efficacy and ADR of Houttuynia cordata eye drops combined with Olopatadine eye drops in the treatment of allergic conjunctivitis. METHODS:160 eyes with allergic conjunctivitis were randomly divided into observation group and control group,with 80 eyes in each group. The control group was given olopatadine eye drops,and observa-tion group was additionally given H. cordata eye drops(medication interval>10 min)on the basis of control group. Both groups were treated for 14 days. Symptoms and signs of 2 groups were observed and scored before treatment and 14 d after treatment. Ef-fective rates of 2 groups were calculated,and the occurrance of ADR was observed. RESULTS:Compared with before treatment, symptoms and sings score of 2 groups were decreased,with statistical significance (P<0.01 or P<0.05);the decrease of two score in observation group were more significant than in control group,with statistical significance (P<0.05);effective rates of control group and observation group were 37.50%and 77.50%,with statistical significance(P<0.05). CONCLUSIONS:H. corda-ta eye drops combined with olopatadine eye drops can ameliorate clinical symptoms and signs of allergic conjunctivitis patients sig-nificantly,and improve therapeutic efficacies without obvious ADR.
