Efficacy Observation of TanshinoneⅡA Sulfonate Combined with Alprostadil in the Treatment of Acute Cere-bral Infarction

VernacularTitle:丹参酮ⅡA磺酸钠联合前列地尔治疗急性脑梗死的疗效观察
Author: Han BAO ; Tao LU ; Chen TAO
Publication Type:Journal Article
Keywords: TanshinoneⅡA sulfonate; Alprostadil; Cerebral infarction
From: China Pharmacy 2015;(23):3287-3288,3289
CountryChina
Language:Chinese
Abstract: OBJECTIVE:To observe clinical efficacy and safety of tanshinone ⅡA sulfonate combined with alprostadil in the treatment of acute cerebral infarction. METHODS:56 patients with acute cerebral infarction were randomly divided into treatment group(36 cases)and control group(20 cases). Control group was given tanshinone ⅡA sulfonate 60 mg intravenously,qd,for 10 days. Treatment was additionally given Alprostadil injection 10 μg intravenously,30 min drop lrote,qd,the two group for 10 days,on the basis of control group. Therapeutic efficacy and BI were observed at the end of a treatment course. RESULTS:The ef-fective rate of treatment group and control group were 91.67% and 75.00%,with statistical significance(P<0.05). BI score of 2 groups after treatment were better than before,and the treatment group was better than the control group after treatment,with statis-tical significance (P<0.05). No obvious ADR wad found in both groups. CONCLUSIONS:Tanshinone ⅡA sulfonate combined with alprostadil is effective in the treatment of acute cerebral infarction with good safety.