Determination of 9 Inorganic Anions in Ganmao Qingre Granules by Ion Chromatography
10.6039/j.issn.1001-0408.2015.18.34
- VernacularTitle:离子色谱法同时测定感冒清热颗粒中9种无机阴离子
- Author:
Weie ZHOU
;
Lijiao YANG
;
Wei XIE
;
Shoujun JIANG
- Publication Type:Journal Article
- Keywords:
Ion chromatography;
Ganmao qingre granules;
Inorganic anion
- From:
China Pharmacy
2015;(18):2546-2548,2549
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish the ion chromatography for the mass fractions of 9 inorganic anions (fluoride ion,for-mate radical,chloride ion,nitrite radical,bromide ion,nitrate radical,sulfate radical,oxalate radical and phosphate radical) in Ganmao qingre granules. METHODS:Ion chromatograph was used. The column was Ion Pac AS11-HC with the mobile phase of po-tassium hydroxide solution by gradient elution(concentration:30 mmol/L,time:15 min),the column temperature was room tem-perature,the volume was 25 μl. RESULTS:The 9 inorganic anions were basically achieved separation and had good linear relation-ship with r of 0.999 2-0.999 9,respectively;RSDs of precision,stability and reproducibility tests were less than 3.50%. Average re-covery was 92.47%-103.51%(RSD=0.42%-3.41%,n=6),respectively. CONCLUSIONS:The established method is fast,accu-rate,sensitive and repeatable and can be used for the determination of 9 inorganic anions in Ganmao qingre granules.
