Clinical Observation of Sanqi Shengji Ointment Preventing Skin Flap Necrosis
10.6039/j.issn.1001-0408.2015.20.24
- VernacularTitle:三七生肌膏预防皮瓣坏死的临床观察
- Author:
Zongchao LI
;
Wei YE
- Publication Type:Journal Article
- Keywords:
Sanqi shengji ointment;
Skin flap necrosis;
Prevention effect
- From:
China Pharmacy
2015;(20):2806-2807,2808
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the clinical effects of Sanqi shengji ointment (SQSJO) preventing skin flap necrosis. METHODS:75 cases of local flap transfer in head and facial operation were randomly divided into blank group,treatment group, control group and with 25 cases in each group. After surgery,except for conventional treatment,treatment group was coated with SQSJO additionally;control group was additionally treated with rh-bFGF. The dressing was changed with iodophor in blank group conventionally till the wound healed. The skin flap necrosis,healing course,local skin temperature,swelling disappearance time and wound healing time were observed and compared among 3 groups after surgery. RESULTS:Compared with blank group,the incidence of skin flap necrosis decreased significantly in other 2 groups,there was statistical significance(P<0.05). There was sta-tistically significant difference in healing rate ameng 3 grups(P<0.05);there was no statistical significance in local skin tempera-ture among 3 groups after surgery (P>0.05);the flap swelling disappearance time and wound healing time of treatment group were significantly shorter than those of control group and blank group;there was statistical significance (P<0.05). CONCLU-SIONS:SQSJO can prevent skin flap necrosis accurately after flap transfer,and has no significant difference from rh-bFGF in pre-vention effect. Moreover,it is better than rh-bFGF in improving local swelling and shortening wound healing.
