Application of Airway Secretions Expurgation Cluster Management in Oxygen-driven Aerosol Inhalation Therapy
10.6039/j.issn.1001-0408.2015.20.26
- VernacularTitle:气道分泌物廓清技术集束化管理在氧气驱动雾化吸入疗法中的应用
- Author:
Yu LIU
;
Zhihe WANG
;
Xiaoling HE
;
Ying WANG
;
Xiu MU
;
Sijing LU
- Publication Type:Journal Article
- Keywords:
Airway secretions expurgation cluster management;
Oxygen-driven aerosol inhalation;
Chronic obstructive pulmo-nary disease
- From:
China Pharmacy
2015;(20):2811-2812,2813
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the efficacy and safety of the application of airway secretions expurgation cluster manage-ment in oxygen-driven aerosol inhalation. METHODS:280 patients with chronic obstructive pulmonary disease in the Respiratory Second Division of our hospital from Mar. 2012 to Dec. 2013 were randomly divided into group A,B,C and D,with 70 cases in each group.Group A and B were treated with compound isopropyl bromide 2 ml+nomal saline 5 ml,10 min/time,twice a day,and 6 L/min oxygen-driven aerosol inhalation for 7 days;group C and Dreceived Ambroxol hydrochloride injection 15 ml+normal saline 5 ml,10 min/time,twice a day,and 6 L/min oxygen-driven aerosol inhalatiom for 7 days. group A and C were treatment groups, group B and D were control groups. Two treatment groups inhaled compound medications while the application of airway secretions expurgation cluster management. Two control groups inhaled compound medications with single effective cough guidance. RE-SULTS:Compared with control groups,the patients in treatment groups eliminated more phlegm,had lower (PaCO2)and higher (PaO2),also had a shorter hospitalization period,with significant difference(P<0.05). CONCLUSIONS:Airway secretions expur-gation cluster management technology is a simple,safe and effective method,especially in patients with chronic obstructive pulmo-nary disease in oxygen-driven inhalation therapy.
