Analysis of the Application of Antihypertensive Drugs in 34 Hospitals of Wuhan City during 2011 to 2013

VernacularTitle:武汉地区34家医院2011－2013年抗高血压药应用分析
Author: Xiping LI ; Zaoqin YU ; Dong LIU
Publication Type:Journal Article
Keywords: Antihypertensive drugs; Defined daily dose; DDDs; DDC
From: China Pharmacy 2015;(20):2748-2750,2751
CountryChina
Language:Chinese
Abstract: OBJECTIVE:To provide reference for rational clinical use of drugs and sound management thereof. METH-ODS:The relative data of antihypertensive drugs applied in 34 hospitals in Wuhan city during 2011 and 2013 were analyzed sta-tistically by using the analytical method of the Defined Daily Dose(DDD)recommended by WHO. RESULTS:Both consump-tion amount and DDDs of antihypertensive drugs in Wuhan city were increasing during 2011 and 2013,where calcium-channel blockers(CCB)enjoyed the largest consumption amount and the highest DDDs,with the constituent ratio of over 40% respec-tively,followed by angiotensinⅡreceptor antagonist (ARB) and angiotensin converting enzyme inhibitors (ACEIs). The con-sumption amount and DDDs of new compound preparation also increased. Top three single drugs in terms of consumption amount were amlodipine,levamlodipine and valsartan,while amlodipine,nifedipine and felodipine ranked the top three in DDDs list. CONCLUSIONS:Wide usage of antihypertensive drugs in Wuhan City are respectively CCB,ARB,ACEI,adrener-gic receptor blockers and diuretics,which are applied in current principle of antihypertensive drugs use and basically rational in clinical application.