Advances in technology of minimal residual disease detection in childhood acute myeloid leukemia
10.3760/cma.j.issn.1673-4408.2016.10.005
- VernacularTitle:儿童急性髓系白血病微小残留病检测技术的应用进展
- Author:
Qing GUO
- Publication Type:Journal Article
- Keywords:
Childhood;
Acute myeloid leukemia;
Minimal residual disease;
Detecting technology
- From:
International Journal of Pediatrics
2016;43(10):760-762,768
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,the efficacy of treatment of childhood acute myeloid leukemia (AML) has been greatly improved,but relapse is still a main factor affecting prognosis.A large number of studies have indicated that the level of minimal residual disease(MRD) is closely related to the relapse of AML,and it also has great significance to predict the prognosis of the disease and guide treatment selection.The hot spot in MRD research is searching for detecting methods with high specificity and sensitivity,simple and suitable characteristics.This article aims to review the latest progress of MRD detecting technology of AML.
