Changes in the Demographics and Prognoses of Patients with Resected Non-Small Cell Lung Cancer: A 20-Year Experience at a Single Institution in Korea.
10.3346/jkms.2012.27.12.1486
- Author:
Jin Gu LEE
1
;
Chang Young LEE
;
Mi Kyung BAE
;
Chun Sung BYUN
;
Dae Joon KIM
;
Kyung Young CHUNG
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Seoul, Korea. kychu@yuhs.ac
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Demography;
Prognosis;
Change;
Carcinoma;
Non-Small Cell Lung Cancer
- MeSH:
Adolescent;
Adult;
Aged;
Aged, 80 and over;
Carcinoma, Non-Small-Cell Lung/*diagnosis/mortality/surgery;
Child;
Demography;
Female;
Humans;
Lung Neoplasms/*diagnosis/mortality/surgery;
Male;
Middle Aged;
Neoplasm Staging;
Prognosis;
Republic of Korea;
Retrospective Studies;
Survival Rate;
Young Adult
- From:Journal of Korean Medical Science
2012;27(12):1486-1490
- CountryRepublic of Korea
- Language:English
-
Abstract:
The demographics and prognosis of non-small cell lung cancer patients have changed during the last few decades. We conducted this study to assess the change in demographics and prognosis in resected non-small cell lung cancer patients during a 20-yr single-institution study in Korea. We retrospectively reviewed the medical records of 2,076 non-small cell lung cancer patients who underwent pulmonary resection between 1990 and 2009. Their clinical characteristics and survival were analyzed over a five-year period. With time, the proportions of female, adenocarcinoma, stage IA, and lobectomy patients increased, whereas the proportions of male, squamous cell carcinoma, stage IIIA, and pneumonectomy patients decreased. These demographic changes caused improved prognosis. The five-year survival rate of all patients was 53.9%. The five-year survival rate increased from 31.9% in 1990-1994, to 43.6% in 1995-1999, 51.3% in 2000-2004, and 69.7% in 2005-2009 (P < 0.001). In conclusion, among patients with resected non-small cell lung cancer, the proportions of female, adenocarcinoma, stage IA, and lobectomy patients have increased, and the five-year survival rate has gradually improved during the last 20 yr in Korea.
