Dosimetry Study of IMRT and 3D-CRT Radiotherapies for Patients with Upper Esophageal Carcinoma

VernacularTitle:胸上段食管癌调强放疗和三维适形放疗剂量学研究
Author: Xiaolin GE ; Xinchen SUN ; Wenzhang CHEN ; Yikun LI
Publication Type:Journal Article
Keywords: esophageal carcinoma; 3-dimensional conformal radiation therapy; intensiry modulated radiation therapy; dosimetry
From: Chinese Journal of Medical Physics 2010;27(2):1708-1711,1720
CountryChina
Language:Chinese
Abstract: Objective: To compare the difference of intensity modulated radiation therapy (IMRT),3-D imensional conformal radiation therapy (3DCRT) for patients with upper esophageal carcinoma. Methods: Ten patients with upper esophageal carcinoma were treated by intensity modulated radiation therapy and 3-D imensional conformal radiation therapy at the same TPS, the difference of exposure dose between target area and critical organ was compared by dose volume histogram(DVH) with the plan target volume (PTV) must reach 95% of the prescription dose. Results: There was significant difference in dose of 95% plan target volume (PTV) (P <0.05) IMRT better than 3D-CRT. For two target conformal index and the prescription dose coverage of GTV percentage IMRT was better than 3DCRT. IMRT reduced maximum dose of spinal cord (P <0.05). There was no difference in the dose of lung and heart (P >0.05). Compared with 3D-CRT, IMRT planning has better dose distribution and protection of normal tissue. Conclusions: IMRT was better than 3DCRT, IMRT is the best radiation therapy.