Different doses vitamin D to bone metabolism in obese persons after Roux-en-Y gastric bypass

VernacularTitle:不同剂量维生素D对Roux-en-Y胃旁路减重术后骨代谢异常的影响
Author: Qingjiao QI ; Peng CAI ; Qingkai YAN ; Xukai WANG
Publication Type:Journal Article
Keywords: Roux-en-Y gastric bypass; obesity; bone metabolism; vitamin D
From: Journal of Regional Anatomy and Operative Surgery 2016;(2):116-118,119
CountryChina
Language:Chinese
Abstract: Objective To determine the effect of different doses vitamin D supplementation to the change of bone metabolism in 6 months after Roux-en-Y gastric bypass ( RYGB) .Methods The change of body weight and body mass index ( BMI ) in 36 patients in 6 months after RYGB WAS analyzed.Then,the effect of low-dose (n=11,400 IU/day) and high-dose (n=12,1 600 IU/day) vitamin D to the serum calcium,25-hydroxyvitamin D and bone density were observed ,and 15 patients as control .Results In 6 months after RYGB,the body weight and BMI were decreased ,and the differences were statistical significance (P<0.05).The serum calcium,25-hydroxyvitamin D and bone density were increased in high-dose group,and the differences were statistical significance (P<0.05).Conclusion High-dose (1 600 IU/day) vitamin D supplementation is effective to the bone loss of patients undergoing RYGB .