Clinical observation on analgesic effect of flurbiprofen for spastic pain after TUR-P
10.11659/jjssx.1672-5042.201306018
- VernacularTitle:氟比洛芬酯对TUR-P术后膀胱痉挛性疼痛治疗效果的观察
- Author:
Nanhui ZHANG
;
Shiying GUO
;
Long LIU
- Publication Type:Journal Article
- Keywords:
cystospasm;
flurbiprofen axetil;
TUR-P
- From:
Journal of Regional Anatomy and Operative Surgery
2013;(6):625-626,628
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the analgesic effect and its complications of flurbiprofen axetil for spastic pain after transurethral re-section of prostate( TUR-P) . Methods 40 patients who were clinically diagnosed as benign prostatic hyperplasia and underwent TUR-P were randomly divided into the experimental group (n=20)and the control group(n=20). When the postsurgical spastic bladder pain happened, the patients in the experimental group received intravenous drip of flurbiprofen axetil 100 mg with saline 500 mL,and the patients in the con-trol group received intramuscular injection of pethidine hydrochloride 100 mg. If its effect is not good,100 mg bucinnazine hydrochloride were injected. Analgesia efficacy was assessed by visual analog scales( VAS) at 30 min,1 h,2 h,4 h,6 h and 8 h after medication. At the same time,the side-effects and complications were observed and recorded. Results There is no statistical difference between the experimental group and the control group at 30 min,1 h, and 2 h after medication(P>0. 05),but at 4 h,6 h and 8 h after medication,VAS score of the experimental group is obviously lower than that of the control group(P<0. 05). And the incidence of adverse reaction of the experimental group, such as thirst,dizziness,nausea and emesia,was lower than that of the control group(P<0. 05). But there is no significant difference in incidence of the secondary bleeding between the two groups(P>0. 05). Conclusion Intravenous drip of flurbiprofen axetil can be an ef-fective and safe way of curing postsurgical spastic bladder pain after TUR-P.
