Relationships between baseline R2*of BOLD-MRI and Semi-quantitative parameters of DCE-MRI in cervical cancer
10.11659/jjssx.10E015059
- VernacularTitle:宫颈癌DCE-MRI半定量参数与BOLD-MRI基线R2?的相关性研究
- Author:
Wangjing REN
;
Jun ZHAO
;
Yanzhou WANG
;
Mingshan DU
;
Wei CHEN
;
Huicheng XU
- Publication Type:Journal Article
- Keywords:
uterine cervical neoplasms;
magnetic resonance imaging;
hypoxia;
parameter
- From:
Journal of Regional Anatomy and Operative Surgery
2015;(2):154-156,157
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationships between baseline R2? of blood oxygenation level-dependent magnetic resonance imaging(BOLD-MRI) and Semi-quantitative parameters of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI) in cervical cancer,to lay a foundation for the further development of assessing tumor hypoxia techniques. Methods Twenty-four patients with cervical cancer were subjected to DCE-MRI and BOLD-MRI before treatment,Semi-quantitative parameters(SI-I、MER、Tmax、IAUC) of DCE-MRI and the baseline R2?of BOLD-MRI produced by special post-processing softwares,the relationships between baseline R2?of BOLD-MRI and Semi-quantitative parameters of DCE-MRI were analyzed. Results Significant positive correlations were observed between baseline R2?and Tmax(r=0.423,P=0.014),there were no correlation between baseline R2? and SI-I、MER or IAUC(P>0.05). Conclusion Semi-quantitative parameters of DCE-MRI and baseline R2? of BOLD-MRI respectively reflected the oxygenation of tumor in different principle. The combined use of the above parameters is expected to improve the performance for defining tumor hypoxia.
