Correlation of corneal wound quality and different corneal lamellar-cut depths with femtosecond laser for lamel-lar anterior keratoplasty
10.11659/jjssx.04E016091
- VernacularTitle:浅板层角膜移植术中飞秒激光切削深度和角膜创面质量的相关性
- Author:
Ke WANG
;
Jie XIONG
;
Qihui LUO
;
Chenxing ZHANG
- Publication Type:Journal Article
- Keywords:
femtosecond laser;
lamellar keratoplasty;
cutting depth
- From:
Journal of Regional Anatomy and Operative Surgery
2016;25(7):482-486,487
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the corneal wound quality of different corneal lamellar-cut depths with the femtosecond laser for fem-tosecond laser-assisted lamellar anterior keratoplasty so as to provide theoretical basis for the appliation of femtosecond laser.Methods Full lamellar cuts were made on 20 human cadaver corneas through femtosecond laser.The 20 human cadaver corneas were divided into 5 groups according to the relative cutting depth which means ratio of the actual cutting depth and the central cornea thickness of 17% to 21%(100 μm,n =3),31% (n =5),35% (n =5),38% to 40% (n =4),and 45% to 48% (n =3).Scanning electron microscopy images of the cap and bed surfaces were graded for ridge and roughness with a scale of 1 to 5 point (1 =best,5 =worst).And the graft-host match was evaluated by photography and optical coherence tomography in a simulated procedure.Results The ridge scores was correlated with the rela-tive cutting depth (P =0.000 24,R =0.73).The 17% to 21% group had the shallowest cutting depth and the fewest ridges (1.25 point). The score of the 31% group was 2.15 point which was significantly lower than the other groups with deeper cutting depth.The roughness score ranged from 2.19 to 3.08 among the 5 group without singnificant difference (P >0.05).Conclusion The femtosecond laser produced more ridges in deeper lamellar cuts and the relative cutting depth of 31% might produce an adequate surface quality for femtosecondlaser-as-sisted lamellar anterior keratoplasty.
