A New Alkaloid from Bombycis Feculae and Its a-Glucosidase Inhibitory Activity
10.3969/j.issn.1674-6384.2011.01.013
- Author:
Yuanyuan ZHU
;
Zhihong WANG
;
Hui QI
;
Gang BAI
- Publication Type:Journal Article
- Keywords:
alkaloid;
Bombycis Feculae;
1-deoxynojirimycin;
1,3-dideoxygalatonojirimycin;
a-glucosidase inhibitor
- From:
Chinese Herbal Medicines
2011;03(1):64-65,74
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the chemical constituents of Bombycis Feculae. Methods Chemical constituents were isolated BPLC-ELSD. The structures of the isolated compounds were determined by spectral means. Results Two compounds were isolated and identified as 1-deoxynojirimycin (1) and (2R,3R,5R)-2-(hydroxymethyl)piperidine-3,5-diol, named as 1,3-dideoxygalatonojirimycin (2). Conclusion Compound 2 is a new alkaloid. The extract of Bombycis Feculae, compound 1 and compound 2 show inhibitory activities against a-glucosidase.
