CORRELATIONS BETWEEN SERUM 25 (OH) D LEVELS AND SUBCORTICAL ARTERIO-SCLEROTIC ENCEPHALOPATHY
10.3969/j.issn.1671-332X.2015.03.010
- VernacularTitle:皮层下动脉硬化性脑病和维生素D水平的相关性研究
- Author:
Wenbin YANG
;
Jianwei ZHUANG
;
Hong LIN
- Publication Type:Journal Article
- Keywords:
Subcortical arteriosclerotic encephalopathy;
Vitamin D;
Serum 25(OH)D;
Correlation
- From:
Modern Hospital
2015;(3):36-37,40
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlations between the levels of serum 25 ( OH) D and age, blood sugar, blood lipid, blood pressure and insulin levels in patients with subcortical arteriosclerotic encephalopathy . Methods A total of 100 patientswith subcortical arteriosclerotic encephalopathy ( SAE) and 50 healthy persons were enrolled in the study.ELISA was adopted to determine serum 25(OH)D levels in two groups.Meantime, fasting glu-cose, blood lipid, blood pressure and insulin levels were measured and compared between two groups .Results The systolic blood pressure , diastolic blood pressure , fasting glucose , total cholesterol and insulin levels in SAE patients were significantly higher than those in the healthy control (p<0.05).The serum 25(OH)D levels in SAE patients were significantly lower than that in the healthy control (p<0.01).There were no significant differences in triglycer-ide and lipoprotein between two groups (p>0.05).The serum 25(OH)D levelswere negatively related with age, SBP, DBP and fasting glucose(p<0.05,p<0.01) but not correlative with TC, TG, LDL, HDL, and insulin levels in SAE patients.Conclusion The serum 25(OH)D levels in SAE patients are reducedby playing a regulative role in the occurrence and development of SAE throughaffectingthe energy metabolism .
