Diagnostic value of serum IMA,Lp-PLA2 and cTnI in acute coronary syndrome
10.3969/j.issn.1673-4130.2016.16.022
- VernacularTitle:血清IM A、L p-PL A2、cT nI对急性冠状动脉综合征的诊断价值
- Author:
Dan HUANG
;
Zhenzhen WEI
- Publication Type:Journal Article
- Keywords:
acute coronary syndrome;
ischemia-modified albumin;
lipoprotein-associated phospholipase A2;
cardiac tropo-nin I
- From:
International Journal of Laboratory Medicine
2016;37(16):2263-2264,2267
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnostic value of serum ischemia‐modified albumin (IMA) ,lipoprotein‐associated phos‐pholipase A2 (Lp‐PLA2) and cardiac troponin I (cTnI) in acute coronary syndrome (ACS) .Methods The levels of serum IMA , Lp‐PLA2 and cTnI were detected in 138 cases of ACS ,including 79 cases of acute myocardial infarction (AMI) ,59 cases of unstable angina pectoris (UAP) ,and the detection results were compared with those in 50 individuals undergoing physical examination(con‐trol group) .The levels of serum IMA ,Lp‐PLA2 and cTnI were compared among various groups .The receiver characteristic curve (ROC) was drawn to evaluate the diagnostic value of IMA ,Lp‐PLA2 and cTnI in ACS .Results The levels of serum IMA ,Lp‐PLA2 and cTnI in patients with UAP and AMI were higher than those in the healthy control group ,and there was statistical differ‐ence between them(t=7 .286 ,8 .589 ,8 .952 ,P<0 .01) .Comparing with the UAP group ,the levels of serum IMA ,Lp‐PLA2 and cTnI in the AMI group were significantly increased(t=4 .063 ,5 .987 ,2 .062 ,P<0 .05) .In the ROC curve analysis ,the area under ROC curve (AUC) of IMA ,Lp‐PLA2 and cTnI were 0 .821 ,0 .843 and 0 .852 respectively .Conclusion The levels of serum IMA , Lp‐PLA2 and cTnI can be used for monitoring and early diagnosis of ACS .
