Diagnostic value of combined detection of serum NSE,CYFRA21-1,CA50,SCC and CEA in patients with esophageal squamous cell carcinoma
10.3969/j.issn.1673-4130.2016.17.004
- VernacularTitle:食管鳞癌患者血清NSE、CYFRA21-1、CA50、SCC和CEA联合检测的诊断价值
- Author:
Wei FAN
;
Chengdong SHI
;
Ping CHEN
- Publication Type:Journal Article
- Keywords:
tumor markers;
esophageal squamous cell carcinoma;
sensitivity;
diagnostic efficiency;
combined detection
- From:
International Journal of Laboratory Medicine
2016;37(17):2369-2370,2373
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the diagnostic value of single detection and combined detection of serum NSE ,CYFRA21‐1 , CA50 ,SCC and CEA in the patients with esophageal squamous cell carcinoma .Methods The single detection and combined detec‐tion of serum NSE ,CYFRA21‐1 ,CA50 ,SCC and CEA levels were measured in 110 cases of esophageal squamous cell carcinoma and 101 health controls in our hospital from October 2013 to October 2015 .The detection results were statistically analyzed . Results The positive rate and expression levels of serum NSE ,CYFRA21‐1 ,CA50 ,SCC and CEA in the esophageal squamous cell carcinoma group were higher than those in the health control group with statistical significance(P<0 .05) .The sensitivity and diag‐nostic efficiency of combined detection of NSE ,CYFRA21‐1 ,CA50 ,SCC and CEA for diagnosing esophageal squamous cell carcino‐ma were 93 .64% and 86 .73% respectively .Conclusion The 5 tumor markers combined detection of serum NSE ,CYFRA21‐1 , CA50 ,SCC and CEA can improve the sensitivity and diagnostic efficiency for diagnosing esophageal squamous cell carcinoma .
